It must be the methotrexate. It has to be. What else could be causing this pain?? It feels like the soles o my feet ache and burn! All day, all night, sore feet, feels like walking on broken glass. And they are so swollen. I purchased 2 wooden shoe stretchers online. I have been cranking them open to try and fit my swollen feet inside. I have bought so many insoles for my shoes trying to provide some comfort when I walk or take a step. The worst hour is first thing in the morning when I step out of bed, it feels like I have been walking barefoot on hot cement all night. I cry out in pain each morning. Towards the end of the day the balls of my feet are so puffy and swollen. Not the top, or my ankles though, just the balls of the soles. UUGH………..seems like I should be getting relief by now with this medication. i wish I could say these aching feet were from training for a race or a marathon. But, I can’t. I have a doctor’s appt on Tuesday. I will see what he has to say.